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UPDATED: 2:51 P.M. ET:
Rex Ryan just said on @WFAN660 Sammy Watkins is likely out this week as well. A little stronger than he stated earlier.
— Mike Garafolo (@MikeGarafolo) September 30, 2015
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The Buffalo Bills could be without at least one of their two major offensive weapons on Sunday against the New York Giants, with running back LeSean McCoy and wide receiver Sammy Watkins both in doubt right now, according to Bills coach Rex Ryan.
Rex: "Will Sammy (Watkins) play? I'm not sure. Shady (McCoy), doesn't look good."
— Vic Carucci (@viccarucci) September 30, 2015
Rex says McCoy "has hamstring issue. Not 100 pct. Holding him out of practice. Real possibilty he won't play he won't play in this game."
— Vic Carucci (@viccarucci) September 30, 2015
McCoy, of course, was a Giants nemesis during his time with the Philadelphia Eagles. McCoy has 1,036 yards on 199 carries (5.21 yards per carry) in 12 games against the Giants. He has five 100+ yard rushing games against New York
#Bills trainer talks w LeSean McCoy at practice. pic.twitter.com/OIXhb71dT5
— Vic Carucci (@viccarucci) September 30, 2015
The Bills, though, have fifth-round pick Karlos Williams averaging 7.8 yards per carry (24 rushes, 186 yards).
Watkins has seven catches for 99 yards in three games.Watkins is dealing with a calf injury.
Ryan is scheduled to hold a conference call with New York media at some point today. More from the talkative Bills coach when that happens.