The Giants placed starting safety Jason Pinnock, who had previously been ruled out of the game with a toe injury suffered last week against the Los Angeles Rams, on injured reserve.
That move left the Giants with two open roster spots after Tyre Phillips, who tore a quad tendon last week, was placed on injured reserve.
To fill those openings, the Giants signed quarterback Jacob Eason and tight end Tyree Jackson from their practice squad to the 53-man roster.
Eason, who has been on and off the practice squad this season, was signed as a third, emergency quarterback. Starter Tyrod Taylor was limited throughout the week with a back injury.
Jackson, who has been on the practice squad all season, played in two prior games for the Giants with one start. He has played 18 offensive snaps.
The Giants also elevated placekicker Mason Crosby and offensive tackle Yodny Cajuste from the practice squad.