Both Andrew Thomas and Daniel Jones have been ruled out by head coach Brian Daboll. He also ruled center John Michael Schmitz, tackle Matt Peart, and edge defender Azeez Ojulari out as well.
Jones suffered his neck injury in last week’s loss to the Miami Dolphins. And while there was optimism that he could avoid missing time, Daboll said that Jones felt “a bit more sore” during the week, and he didn’t practice on Wednesday or Thursday.
“I think he’s getting better but not good enough to play for this game,” Daboll said.
Tyrod Taylor will start at quarterback for the Giants.
“Tyrod’s a pro,” Daboll said. “He comes out every day and approaches it the right way in the backup situation, but he always approaches it as if he’s the starter, so he’s had a good week, he’s prepared well but he does that every week.”
Left tackle Andrew Thomas suffered a hamstring injury back in week one, which he aggravated in practice a week ago, and hasn't practiced since.
Schmitz and backup Peart are also recovering from a shoulder injuries, while right tackle Evan Neal was limited with an ankle injury. Daboll did not give an update with regards to Neal's injury.
Ojulari has also missed practice with an ankle injury,
Meanwhile, tight end Darren Waller was limited with his own ankle injury.
In a bit of good news, the Giants could get Saquon Barkley back from his high ankle sprain. Barkley has been limited in practice this week, but has been more involved more each day of practice.
Giants-Bills final injury report
QB Daniel Jones (neck)
OT Andrew Thomas (hamstring)
OT Matt Peart (shoulder)
C John Michael Schmitz (shoulder)
Edge Azeez Ojulari (ankle)
LB Micah McFadden (ankle)
TE Darren Waller (groin)
RB Saquon Barkley (ankle)
RB Gary Brightwell (ankle)
OL Shane Lemieux (groin)
DL D.J. Davidson (knee)
OT Evan Neal (ankle)
CB Dane Jackson (foot)
TE Dalton Kincaid (concussion)
TE Dalton Knos (wrist)