The Indianapolis Colts (6-3) have little time to rebound from an embarrassing 38-8 home loss to the St. Louis Rams as the team travels to Tennessee to face the Titans (4-5), who also must come off of an embarrassing loss of their own to the Jacksonville Jaguars at home. The Titans also lost starting quarterback Jake Locker for the season in their last game, so the team will host the Colts at LP Field on Thursday Night Football with new starter, Ryan Fitzpatrick, at quarterback.
Game Time: 8:25 p.m. ET
TV: NFL Network
Odds: Colts -3
Will Fitzpatrick be able to play better than his earlier starts this season, in which the team went 0-2? Can someone besides T.Y. Hilton step up at receiver for the Colts and help replace the void left by Reggie Wayne's injury? And can the team finally fix whatever is causing its running game led by Trent Richardson to be ineffective? Use this as an Open Thread to discuss the action.