Prince Amukamara, Brandon Jacobs, Mitch Petrus, David Baas, James Brewer, Michael Clayton and Justin Tuck will be inactive today for the New York Giants.

Pat Traina points out that Tuck will be missing his first back-to-back games since 2006. With Jacobs (knee) inactive that means rookie Da'Rel Scott will be suiting up for the first time.

For me, the other surprise here is that Petrus is inactive. I figured Jim Cordle, a backup center just added to the roster this week, would be active. I figured the Giants would also try to keep Petrus active, though, possibly dropping a linebacker like Mark Herzlich.

For Seattle, scratch WR Mike Williams, G Robert Gallery, CB MarcusTrufant, QB J.Portis, CB B.Maxwell, LB M.Smith, and T J.King. The loss of Trufant wil be significant for Seattle's secondary.

Other than the inactives, I'm really curious to see what -- if any -- adjustments the Giants make in run defense today.